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The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides
A systematic study of the thermal and conformational properties of chemically modified G-quadruplexes of different molecularities is reported. The effect of backbone charge and atom size, thymine/uracyl substitution as well as the effect of modification at the ribose 2′-position was analyzed by UV s...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549566/ https://ncbi.nlm.nih.gov/pubmed/15731338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki257 |
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