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Novel Proteasome Inhibitors and Histone Deacetylase Inhibitors: Progress in Myeloma Therapeutics
The unfolded protein response is responsible for the detection of misfolded proteins and the coordination of their disposal and is necessary to maintain the cellular homoeostasis. Multiple myeloma cells secrete large amounts of immunoglobulins, proteins that need to be correctly folded by the chaper...
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| Published in: | Pharmaceuticals (Basel) |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5490397/ https://ncbi.nlm.nih.gov/pubmed/28398261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph10020040 |
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