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Preclinical Evaluation of the Short-Term Toxicity of 4-(N)-Docosahexaenoyl 2′, 2′-Difluorodeoxycytidine (DHA-dFdC)
PURPOSE: This study was designed to test the short-term toxicity of DHA-dFdC in a mouse model and its efficacy in a mouse model of leukemia at or below its repeat-dose maximum tolerated dose (RD-MTD). METHOD: A repeat-dose dose-ranging toxicity study was designed to determine the tolerability of DHA...
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| Publicat a: | Pharm Res |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5488709/ https://ncbi.nlm.nih.gov/pubmed/28352993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-017-2139-x |
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