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Preclinical Evaluation of the Short-Term Toxicity of 4-(N)-Docosahexaenoyl 2′, 2′-Difluorodeoxycytidine (DHA-dFdC)

PURPOSE: This study was designed to test the short-term toxicity of DHA-dFdC in a mouse model and its efficacy in a mouse model of leukemia at or below its repeat-dose maximum tolerated dose (RD-MTD). METHOD: A repeat-dose dose-ranging toxicity study was designed to determine the tolerability of DHA...

詳細記述

保存先:
書誌詳細
出版年:Pharm Res
主要な著者: Valdes, Solange, Naguib, Youssef W., Finch, Rick A., Baze, Wallace B., Jolly, Christopher A., Cui, Zhengrong
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488709/
https://ncbi.nlm.nih.gov/pubmed/28352993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-017-2139-x
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