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Ca(2+) ionophores are not suitable for inducing mPTP opening in murine isolated adult cardiac myocytes
Opening of the mitochondrial permeability transition pore (mPTP) plays a major role in cell death during cardiac ischaemia-reperfusion. Adult isolated rodent cardiomyocytes are valuable cells to study the effect of drugs targeting mPTP. This study investigated whether the use of Ca(2+) ionophores (A...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5487341/ https://ncbi.nlm.nih.gov/pubmed/28655872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04618-4 |
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