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A microRNA signature of response to erlotinib is descriptive of TGFβ behaviour in NSCLC

Our previous work identified a 13-gene miRNA signature predictive of response to the epidermal growth factor receptor (EGFR) inhibitor, erlotinib, in Non-Small Cell Lung Cancer cell lines. Bioinformatic analysis of the signature showed a functional convergence on TGFβ canonical signalling. We hypoth...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Krentz Gober, Madeline, Collard, James P., Thompson, Katherine, Black, Esther P.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482799/
https://ncbi.nlm.nih.gov/pubmed/28646226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04097-7
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