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Controlled Transcription of Exogenous mRNA in Platelets Using Protocells
Transcribing exogenous RNA in eukaryotic cells requires delivering DNA to their nuclei and changing their genome. Nuclear delivery is often inefficient, limiting the potential scope of gene therapy and synthetic biology. These challenges may be overcome by techniques that allow for extranucleate tra...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5482712/ https://ncbi.nlm.nih.gov/pubmed/26368852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201506500 |
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