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Controlled Transcription of Exogenous mRNA in Platelets Using Protocells

Transcribing exogenous RNA in eukaryotic cells requires delivering DNA to their nuclei and changing their genome. Nuclear delivery is often inefficient, limiting the potential scope of gene therapy and synthetic biology. These challenges may be overcome by techniques that allow for extranucleate tra...

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Bibliografiska uppgifter
I publikationen:Angew Chem Int Ed Engl
Huvudupphovsmän: Chan, Vivienne, Novakowski, Stefanie K., Law, Simon, Klein-Bosgoed, Christa, Kastrup, Christian J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482712/
https://ncbi.nlm.nih.gov/pubmed/26368852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201506500
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