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Controlled Transcription of Exogenous mRNA in Platelets Using Protocells

Transcribing exogenous RNA in eukaryotic cells requires delivering DNA to their nuclei and changing their genome. Nuclear delivery is often inefficient, limiting the potential scope of gene therapy and synthetic biology. These challenges may be overcome by techniques that allow for extranucleate tra...

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Detalles Bibliográficos
Publicado en:Angew Chem Int Ed Engl
Autores principales: Chan, Vivienne, Novakowski, Stefanie K., Law, Simon, Klein-Bosgoed, Christa, Kastrup, Christian J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482712/
https://ncbi.nlm.nih.gov/pubmed/26368852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201506500
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