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A metabolic function for phospholipid and histone methylation
S-adenosylmethionine (SAM) is the methyl donor for biological methylation modifications that regulate protein and nucleic acid functions. Here we show that methylation of a phospholipid, phosphatidylethanolamine (PE), is a major consumer of SAM. The induction of phospholipid biosynthetic genes is ac...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5482412/ https://ncbi.nlm.nih.gov/pubmed/28366644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.02.026 |
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