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Metformin ameliorates hepatic steatosis and improves the induction of autophagy in HFD-induced obese mice
The present study aimed to investigate the effect of metformin on the induction of autophagy in the liver and adipose tissues of a mouse model of obesity. C57BL/6J mice were fed a high-fat diet (HFD) for 12 weeks to induce obesity-associated hepatic steatosis, and treated with metformin (150 mg/kg/d...
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| Publicado no: | Mol Med Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5482143/ https://ncbi.nlm.nih.gov/pubmed/28560428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6637 |
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