Genetic Mutations and Epigenetic Modifications: Driving Cancer and Informing Precision Medicine

Cancer treatment is undergoing a significant revolution from “one-size-fits-all” cytotoxic therapies to tailored approaches that precisely target molecular alterations. Precision strategies for drug development and patient stratification, based on the molecular features of tumors, are the next logic...

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Bibliographic Details
Published in:Biomed Res Int
Main Authors: Coyle, Krysta Mila, Boudreau, Jeanette E., Marcato, Paola
Format: Artigo
Language:Inglês
Published: Hindawi 2017
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480027/
https://ncbi.nlm.nih.gov/pubmed/28685150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9620870
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