ZEB1 induces ER-α promoter hypermethylation and confers antiestrogen resistance in breast cancer

Antiestrogen resistance is a major obstacle to endocrine therapy for breast cancers. Although reduced estrogen receptor-α (ER-α) expression is a known contributing factor to antiestrogen resistance, the mechanisms of ER-α downregulation in antiestrogen resistance are not fully understood. Here, we r...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Jianbo, Zhou, Chen, Jiang, Huimin, Liang, Lin, Shi, Wen, Zhang, Quansheng, Sun, Peiqing, Xiang, Rong, Wang, Yue, Yang, Shuang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477580/
https://ncbi.nlm.nih.gov/pubmed/28383555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.154
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