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177.2 Mutations in the Neuregulin-ErbB4 Pathway Alter Dopaminergic Balance and Regulate Behaviors Relevant to Schizophrenia

Background: Neuregulin-1 (NRG1) and ErbB4 receptor variants are associated with schizophrenia and its endophenotypes. While most studies have focused on NRG1 association with Scz, little is known about its closest homologue NRG2. Because the dopamine (DA) dysbalance and NMDA receptor hypofunction hy...

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Detalles Bibliográficos
Publicado en:Schizophr Bull
Main Authors: Buonanno, Andres, Skirzewski, Miguel
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475708/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.249
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