Vitamin A mediates conversion of monocyte-derived macrophages into tissue resident macrophages during alternative activation

Whether activated inflammatory macrophages can adopt features of tissue resident macrophages and what mechanisms mediate this phenotypic conversion remain unclear. Here we show that vitamin A was required for phenotypic conversion of interleukin 4 (IL-4)-activated monocyte-derived F4/80(int)CD206(+)...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Immunol
Hlavní autoři: Gundra, Uma Mahesh, Girgis, Natasha M, Gonzalez, Michael A, Tang, Mei San, Van Der Zande, Hendrik J P, Lin, Jian-Da, Ouimet, Mireille, Ma, Lily J, Poles, Jordan A, Vozhilla, Nikollaq, Fisher, Edward A, Moore, Kathryn J, Loke, P’ng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475284/
https://ncbi.nlm.nih.gov/pubmed/28436955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3734
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky