Metabolic basis to Sherpa altitude adaptation

The Himalayan Sherpas, a human population of Tibetan descent, are highly adapted to life in the hypobaric hypoxia of high altitude. Mechanisms involving enhanced tissue oxygen delivery in comparison to Lowlander populations have been postulated to play a role in such adaptation. Whether differences...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Horscroft, James A., Kotwica, Aleksandra O., Laner, Verena, West, James A., Hennis, Philip J., Levett, Denny Z. H., Howard, David J., Fernandez, Bernadette O., Burgess, Sarah L., Ament, Zsuzsanna, Gilbert-Kawai, Edward T., Vercueil, André, Landis, Blaine D., Mitchell, Kay, Mythen, Monty G., Branco, Cristina, Johnson, Randall S., Feelisch, Martin, Montgomery, Hugh E., Griffin, Julian L., Grocott, Michael P. W., Gnaiger, Erich, Martin, Daniel S., Murray, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474778/
https://ncbi.nlm.nih.gov/pubmed/28533386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700527114
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