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Understanding Hematopoietic Stem Cell Development through Functional Correlation of Their Proliferative Status with the Intra-aortic Cluster Architecture
During development, hematopoietic stem cells (HSCs) emerge in the aorta-gonad-mesonephros (AGM) region through a process of multi-step maturation and expansion. While proliferation of adult HSCs is implicated in the balance between self-renewal and differentiation, very little is known about the pro...
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發表在: | Stem Cell Reports |
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Main Authors: | , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Elsevier
2017
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5469869/ https://ncbi.nlm.nih.gov/pubmed/28479304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.04.003 |
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