Understanding Hematopoietic Stem Cell Development through Functional Correlation of Their Proliferative Status with the Intra-aortic Cluster Architecture

During development, hematopoietic stem cells (HSCs) emerge in the aorta-gonad-mesonephros (AGM) region through a process of multi-step maturation and expansion. While proliferation of adult HSCs is implicated in the balance between self-renewal and differentiation, very little is known about the pro...

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Publicado en:Stem Cell Reports
Main Authors: Batsivari, Antoniana, Rybtsov, Stanislav, Souilhol, Celine, Binagui-Casas, Anahi, Hills, David, Zhao, Suling, Travers, Paul, Medvinsky, Alexander
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469869/
https://ncbi.nlm.nih.gov/pubmed/28479304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.04.003
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