Behavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models

Parkinson's disease (PD) is a neurodegenerative disorder with symptoms that progressively worsen with age. Pathologically, PD is characterized by the aggregation of α-synuclein in cells of the substantia nigra in the brain and loss of dopaminergic neurons. This pathology is associated with impa...

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Udgivet i:Front Genet
Main Authors: Maulik, Malabika, Mitra, Swarup, Bult-Ito, Abel, Taylor, Barbara E., Vayndorf, Elena M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468440/
https://ncbi.nlm.nih.gov/pubmed/28659967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2017.00077
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