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Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells

The difficulty in isolating and propagating functional primary cholangiocytes is a major limitation in studying biliary disorders and testing novel therapeutic agents. To overcome this problem, we have developed a platform for the differentiation of human Pluripotent Stem Cells (hPSCs) into function...

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Dettagli Bibliografici
Pubblicato in:Nat Protoc
Autori principali: Sampaziotis, Fotios, de Brito, Miguel Cardoso, Geti, Imbisaat, Bertero, Alessandro, Hannan, Nicholas RF, Vallier, Ludovic
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467722/
https://ncbi.nlm.nih.gov/pubmed/28333915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2017.011
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