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Activation of AMP‐activated protein kinase by metformin ablates angiotensin II‐induced endoplasmic reticulum stress and hypertension in mice in vivo
BACKGROUND AND PURPOSE: Metformin, one of the most frequently prescribed medications for type 2 diabetes, reportedly exerts BP‐lowering effects in patients with diabetes. However, the effects and underlying mechanisms of metformin on BP in non‐diabetic conditions remain to be determined. The aim of...
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| Publicado no: | Br J Pharmacol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5466537/ https://ncbi.nlm.nih.gov/pubmed/28436023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13833 |
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