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Activation of AMP‐activated protein kinase by metformin ablates angiotensin II‐induced endoplasmic reticulum stress and hypertension in mice in vivo
BACKGROUND AND PURPOSE: Metformin, one of the most frequently prescribed medications for type 2 diabetes, reportedly exerts BP‐lowering effects in patients with diabetes. However, the effects and underlying mechanisms of metformin on BP in non‐diabetic conditions remain to be determined. The aim of...
Guardat en:
| Publicat a: | Br J Pharmacol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5466537/ https://ncbi.nlm.nih.gov/pubmed/28436023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13833 |
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