Overexpression of Mitochondrial GTPase MFN2 Represents a Negative Prognostic Marker in Human Gastric Cancer and Its Inhibition Exerts Anti-Cancer Effects

Background: As one of the most common malignancies in the world, little is known about the molecular mechanism underlying gastric cancer (GC) and its progression. In this study, we aimed to investigate the clinical impact of the mitochondrial GTPase mitofusin 2 (MFN2) in GC. Methods: Immunohistochem...

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Udgivet i:J Cancer
Main Authors: Fang, Chia-Lang, Sun, Ding-Ping, Chen, Han-Kun, Lin, Chih-Chan, Hung, Shih-Ting, Uen, Yih-Huei, Lin, Kai-Yuan
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2017
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Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463429/
https://ncbi.nlm.nih.gov/pubmed/28607589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.17986
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