Adipose tissue dysfunction as a central mechanism leading to dysmetabolic obesity triggered by chronic exposure to p,p’-DDE

Endocrine-disrupting chemicals such as p,p’-dichlorodiphenyldichloroethylene (p,p’-DDE), are bioaccumulated in the adipose tissue (AT) and have been implicated in the obesity and diabetes epidemic. Thus, it is hypothesized that p,p’-DDE exposure could aggravate the harm of an obesogenic context. We...

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Vydáno v:Sci Rep
Hlavní autoři: Pestana, Diogo, Teixeira, Diana, Meireles, Manuela, Marques, Cláudia, Norberto, Sónia, Sá, Carla, Fernandes, Virgínia C., Correia-Sá, Luísa, Faria, Ana, Guardão, Luísa, Guimarães, João T., Cooper, Wendy N., Sandovici, Ionel, Domingues, Valentina F., Delerue-Matos, Cristina, Monteiro, Rosário, Constância, Miguel, Calhau, Conceição
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453948/
https://ncbi.nlm.nih.gov/pubmed/28572628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02885-9
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