Interleukin-6 Deficiency Attenuates Retinal Ganglion Cell Axonopathy and Glaucoma-Related Vision Loss

The pleotropic cytokine interleukin-6 (IL-6) is implicated in retinal ganglion cell (RGC) survival and degeneration, including that associated with glaucoma. IL-6 protects RGCs from pressure-induced apoptosis in vitro. However, it is unknown how IL-6 impacts glaucomatous degeneration in vivo. To stu...

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Udgivet i:Front Neurosci
Main Authors: Echevarria, Franklin D., Formichella, Cathryn R., Sappington, Rebecca M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450377/
https://ncbi.nlm.nih.gov/pubmed/28620279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00318
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