Rho-Kinase/ROCK as a Potential Drug Target for Vitreoretinal Diseases

Rho-associated kinase (Rho-kinase/ROCK) was originally identified as an effector protein of the G protein Rho. Its involvement in various diseases, particularly cancer and cardiovascular disease, has been elucidated, and ROCK inhibitors have already been applied clinically for cerebral vasospasm and...

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Bibliographic Details
Published in:J Ophthalmol
Main Authors: Yamaguchi, Muneo, Nakao, Shintaro, Arima, Mitsuru, Wada, Iori, Kaizu, Yoshihiro, Hao, Feng, Yoshida, Shigeo, Sonoda, Koh-hei
Format: Artigo
Language:Inglês
Published: Hindawi 2017
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449758/
https://ncbi.nlm.nih.gov/pubmed/28596919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/8543592
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