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Astrocytes locally translate transcripts in their peripheral processes

Local translation in neuronal processes is key to the alteration of synaptic strength necessary for long-term potentiation, learning, and memory. Here, we present evidence that regulated de novo protein synthesis occurs within distal, perisynaptic astrocyte processes. Astrocyte ribosomal proteins ar...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Sakers, Kristina, Lake, Allison M., Khazanchi, Rohan, Ouwenga, Rebecca, Vasek, Michael J., Dani, Adish, Dougherty, Joseph D.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441704/
https://ncbi.nlm.nih.gov/pubmed/28439016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617782114
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