Teng-Long-Bu-Zhong-Tang induces p21-dependent cell senescence in colorectal carcinoma LS174T cells via histone acetylation

Teng-Long-Bu-Zhong-Tang (TLBZT) is a Chinese herbal formula for colorectal carcinoma treatment. TLBZT effectively induces cell senescence in colorectal carcinoma, accompanied by p21 upregulation. In this study, we further explored the role of p21 in TLBZT-induced cell senescence, as well as the mech...

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Bibliographic Details
Published in:J Exp Pharmacol
Main Authors: Hu, Bing, An, Hong-Mei, Wang, Shuang-Shuang, Zheng, Jia-Lu, Yan, Xia, Huang, Xiao-Wei, Tian, Jian-Hui
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2017
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441675/
https://ncbi.nlm.nih.gov/pubmed/28572741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JEP.S129272
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