Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin

Little is known about hematopoietic stem cell (HSC) development from mesoderm. To gain more information on the intraembryonic HSC site of origin, we purified multipotent hematopoietic progenitors from the aorta–gonads–mesonephros (AGM) of mice. This population, expressing c-Kit, AA4.1, CD31, and CD4...

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Main Authors: Bertrand, Julien Y., Giroux, Sébastien, Golub, Rachel, Klaine, Michèle, Jalil, Abdelali, Boucontet, Laurent, Godin, Isabelle, Cumano, Ana
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC544043/
https://ncbi.nlm.nih.gov/pubmed/15623562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402270102
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