Synthesis, docking study and biological evaluation of some new thiourea derivatives bearing benzenesulfonamide moiety

BACKGROUND: A series of novel N-(2, 6-dimethoxypyrimidin-4-yl)-4-(3-(aryl)thioureido) benzenesulfonamides 3a–t was synthesized by the addition of N-(2,6-dimethoxypyrimidin-4-yl)-4-isothiocyanatobenzenesulfonamide 2 to the appropriate aromatic amine. The structures of the synthesized compounds were i...

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Bibliographic Details
Published in:Chem Cent J
Main Authors: Ghorab, Mostafa M., El-Gaby, Mohamed S. A., Soliman, Aiten M., Alsaid, Mansour S., Abdel-Aziz, Marwa M., Elaasser, Mahmoud M.
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438335/
https://ncbi.nlm.nih.gov/pubmed/29086825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-017-0271-7
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