Phospholipase C-related but catalytically inactive proteins regulate ovarian follicle development

Phospholipase C-related but catalytically inactive proteins PRIP-1 and -2 are inositol-1,4,5-trisphosphate binding proteins that are encoded by independent genes. Ablation of the Prip genes in mice impairs female fertility, which is manifested by fewer pregnancies, a decreased number of pups, and th...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Matsuda, Miho, Hirata, Masato
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437242/
https://ncbi.nlm.nih.gov/pubmed/28360101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.759928
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