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Analyses of publicly available genomics resources define FGF-2-expressing bladder carcinomas as EMT-prone, proliferative tumors with low mutation rates and high expression of CTLA-4, PD-1 and PD-L1

Fibroblast growth factor 2 (FGF-2) is overexpressed in a subset of invasive bladder carcinomas and its overexpression correlates with poor prognosis. Analyses of publicly available databases addressing the molecular mechanisms that may be responsible for the poor prognosis of these tumors, revealed...

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Pubblicato in:Signal Transduct Target Ther
Autori principali: McNiel, Elizabeth A, Tsichlis, Philip N
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431749/
https://ncbi.nlm.nih.gov/pubmed/28515962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2016.45
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