HO-1/EBP interaction alleviates cholesterol-induced hypoxia through the activation of the AKT and Nrf2/mTOR pathways and inhibition of carbohydrate metabolism in cardiomyocytes

Heme oxygenase-1 (HO-1) is an inducible and cytoprotective enzyme that provides a defense against oxidant damage. The present study screened 137 HO-1/interacting proteins using a profound co-immunoprecipitation (Co-IP) coupled with proteomics, and profiled the global HO-1 interactome network, includ...

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Veröffentlicht in:Int J Mol Med
Hauptverfasser: Jin, Xiaohan, Xu, Zhongwei, Cao, Jin, Yan, Rui, Xu, Ruicheng, Ran, Ruiqiong, Ma, Yongqiang, Cai, Wei, Fan, Rong, Zhang, Yan, Zhou, Xin, Li, Yuming
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428940/
https://ncbi.nlm.nih.gov/pubmed/28487965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.2979
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