NLRX1 negatively modulates type I IFN to facilitate KSHV reactivation from latency

Kaposi’s sarcoma-associated herpesvirus (KSHV) is a herpesvirus that is linked to Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL) and multicentric Castleman’s disease (MCD). KSHV establishes persistent latent infection in the human host. KSHV undergoes periods of spontaneous reactivation wher...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Ma, Zhe, Hopcraft, Sharon E., Yang, Fan, Petrucelli, Alex, Guo, Haitao, Ting, Jenny P-Y, Dittmer, Dirk P., Damania, Blossom
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426799/
https://ncbi.nlm.nih.gov/pubmed/28459883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006350
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