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Embracing Biological and Methodological Variance in a New Approach to Pre-Clinical Stroke Testing

High-profile failures in stroke clinical trials have discouraged clinical translation of neuroprotectants. While there are several plausible explanations for these failures, we believe that the fundamental problem is the way clinical and pre-clinical studies are designed and analyzed for heterogeneo...

詳細記述

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書誌詳細
出版年:Transl Stroke Res
主要な著者: Kent, Thomas A., Mandava, Pitchaiah
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425098/
https://ncbi.nlm.nih.gov/pubmed/27018014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-016-0463-9
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