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Embracing Biological and Methodological Variance in a New Approach to Pre-Clinical Stroke Testing
High-profile failures in stroke clinical trials have discouraged clinical translation of neuroprotectants. While there are several plausible explanations for these failures, we believe that the fundamental problem is the way clinical and pre-clinical studies are designed and analyzed for heterogeneo...
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Pubblicato in: | Transl Stroke Res |
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Autori principali: | , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2016
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5425098/ https://ncbi.nlm.nih.gov/pubmed/27018014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-016-0463-9 |
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