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Embracing Biological and Methodological Variance in a New Approach to Pre-Clinical Stroke Testing

High-profile failures in stroke clinical trials have discouraged clinical translation of neuroprotectants. While there are several plausible explanations for these failures, we believe that the fundamental problem is the way clinical and pre-clinical studies are designed and analyzed for heterogeneo...

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Bibliografiska uppgifter
I publikationen:Transl Stroke Res
Huvudupphovsmän: Kent, Thomas A., Mandava, Pitchaiah
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425098/
https://ncbi.nlm.nih.gov/pubmed/27018014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-016-0463-9
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