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Embracing Biological and Methodological Variance in a New Approach to Pre-Clinical Stroke Testing

High-profile failures in stroke clinical trials have discouraged clinical translation of neuroprotectants. While there are several plausible explanations for these failures, we believe that the fundamental problem is the way clinical and pre-clinical studies are designed and analyzed for heterogeneo...

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Bibliografische gegevens
Gepubliceerd in:Transl Stroke Res
Hoofdauteurs: Kent, Thomas A., Mandava, Pitchaiah
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425098/
https://ncbi.nlm.nih.gov/pubmed/27018014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-016-0463-9
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