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Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor
Despite decades of research in the epidermal growth factor receptor (EGFR) signalling field, and many targeted anti-cancer drugs that have been tested clinically, the success rate for these agents in the clinic is low, particularly in terms of the improvement of overall survival. Intratumoral hetero...
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Published in: | Oncogene |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
Nature Publishing Group
2017
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5421598/ https://ncbi.nlm.nih.gov/pubmed/28166195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.522 |
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