DeActs: genetically encoded tools for perturbing the actin cytoskeleton in single cells

The actin cytoskeleton is essential for many fundamental biological processes, but tools to directly manipulate actin dynamics are limited to cell-permeable drugs precluding single cell perturbations. Here we describe DeActs, genetically encoded actin-modifying polypeptides, which effectively induce...

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Udgivet i:Nat Methods
Main Authors: Harterink, Martin, da Silva, Marta Esteves, Will, Lena, Turan, Julia, Ibrahim, Adiljan, Lang, Alexander E., van Battum, Eljo Y., Pasterkamp, R. Jeroen, Kapitein, Lukas C., Kudryashov, Dmitri, Barres, Ben A., Hoogenraad, Casper C., Zuchero, J. Bradley
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419720/
https://ncbi.nlm.nih.gov/pubmed/28394337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4257
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