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The importance of tying up loose (DNA) ends
In this issue of Blood, Shi et al(1) demonstrate the importance of Ssb1 and Ssb2, 2 highly conserved single-stranded DNA (ssDNA)–binding proteins, in maintaining hematopoietic stem cell (HSC) genome integrity and blood system function. Strikingly, the authors demonstrate that compound loss of Ssb1 a...
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| Udgivet i: | Blood |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5418642/ https://ncbi.nlm.nih.gov/pubmed/28473409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-03-773184 |
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