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Humoral and Innate Antiviral Immunity as Tools to Clear Persistent HIV Infection

Human immunodeficiency virus (HIV) type 1 uses the CD4 molecule as its principal receptor to infect T cells. HIV-1 integrates its viral genome into the host cell, leading to persistent infection wherein HIV-1 can remain transcriptionally silent in latently infected CD4(+) T cells. On reactivation of...

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Détails bibliographiques
Publié dans:J Infect Dis
Auteurs principaux: Ferrari, Guido, Pollara, Justin, Tomaras, Georgia D., Haynes, Barton F.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410976/
https://ncbi.nlm.nih.gov/pubmed/28520963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw555
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