Hepatocyte nuclear factor 1α suppresses steatosis-associated liver cancer by inhibiting PPARγ transcription

Worldwide epidemics of metabolic diseases, including liver steatosis, are associated with an increased frequency of malignancies, showing the highest positive correlation for liver cancer. The heterogeneity of liver cancer represents a clinical challenge. In liver, the transcription factor PPARγ pro...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Patitucci, Cecilia, Couchy, Gabrielle, Bagattin, Alessia, Cañeque, Tatiana, de Reyniès, Aurélien, Scoazec, Jean-Yves, Rodriguez, Raphaël, Pontoglio, Marco, Zucman-Rossi, Jessica, Pende, Mario, Panasyuk, Ganna
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409083/
https://ncbi.nlm.nih.gov/pubmed/28394260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90327
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