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Epstein–Barr virus-associated gastric cancer reveals intratumoral heterogeneity of PIK3CA mutations

BACKGROUND: Recent whole-genome sequencing identified four molecular subtypes of gastric cancer (GC), of which the subgroup of Epstein–Barr virus-associated GC (EBVaGC) showed a significant enrichment of PIK3CA mutations. We here aimed to validate independently the enrichment of PIK3CA mutations in...

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發表在:Ann Oncol
Main Authors: Böger, C., Krüger, S., Behrens, H. M., Bock, S., Haag, J., Kalthoff, H., Röcken, C.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406766/
https://ncbi.nlm.nih.gov/pubmed/28453696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdx047
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