Competition between Tropomyosin, Fimbrin, and ADF/Cofilin drives their sorting to distinct actin filament networks

The fission yeast actin cytoskeleton is an ideal, simplified system to investigate fundamental mechanisms behind cellular self-organization. By focusing on the stabilizing protein tropomyosin Cdc8, bundling protein fimbrin Fim1, and severing protein coffin Adf1, we examined how their pairwise and co...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Christensen, Jenna R, Hocky, Glen M, Homa, Kaitlin E, Morganthaler, Alisha N, Hitchcock-DeGregori, Sarah E, Voth, Gregory A, Kovar, David R
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2017
Sujets:
Biophysics and Structural Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404920/
https://ncbi.nlm.nih.gov/pubmed/28282023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23152
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