Repurposing Mebendazole as a Replacement for Vincristine for the Treatment of Brain Tumors

The microtubule inhibitor vincristine is currently used to treat a variety of brain tumors, including low-grade glioma and anaplastic oligodendroglioma. Vincristine, however, does not penetrate well into brain tumor tissue, and moreover, it displays dose-limiting toxicities, including peripheral neu...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Mol Med
Auteurs principaux: De Witt, Michelle, Gamble, Alexander, Hanson, Derek, Markowitz, Daniel, Powell, Caitlin, Al Dimassi, Saleh, Atlas, Mark, Boockvar, John, Ruggieri, Rosamaria, Symons, Marc
Format: Artigo
Langue:Inglês
Publié: Feinstein Institute for Medical Research 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403762/
https://ncbi.nlm.nih.gov/pubmed/28386621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2017.00011
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires