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Ursolic acid-mediated changes in glycolytic pathway promote cytotoxic autophagy and apoptosis in phenotypically different breast cancer cells

Plant-derived pentacyclic triterpenotids with multiple biological activities are considered as promising candidates for cancer therapy and prevention. However, their mechanisms of action are not fully understood. In the present study, we have analyzed the effects of low dose treatment (5–20 µM) of u...

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Vydáno v:Apoptosis
Hlavní autoři: Lewinska, Anna, Adamczyk-Grochala, Jagoda, Kwasniewicz, Ewa, Deregowska, Anna, Wnuk, Maciej
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5401707/
https://ncbi.nlm.nih.gov/pubmed/28213701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-017-1353-7
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