Effect of mitochondrially targeted carboxy proxyl nitroxide on Akt-mediated survival in Daudi cells: Significance of a dual mode of action

Vicious cycles of mutations and reactive oxygen species (ROS) generation contribute to cancer progression. The use of antioxidants to inhibit ROS generation promotes cytostasis by affecting the mutation cycle and ROS-dependent survival signaling. However, cancer cells select mutations to elevate ROS...

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Foilsithe in:PLoS One
Main Authors: Variar, Gokul, Pant, Tarun, Singh, Apoorva, Ravichandran, Abinaya, Swami, Sushant, Kalyanaraman, Balaraman, Dhanasekaran, Anuradha
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398517/
https://ncbi.nlm.nih.gov/pubmed/28426671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174546
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