Effect of mitochondrially targeted carboxy proxyl nitroxide on Akt-mediated survival in Daudi cells: Significance of a dual mode of action

Vicious cycles of mutations and reactive oxygen species (ROS) generation contribute to cancer progression. The use of antioxidants to inhibit ROS generation promotes cytostasis by affecting the mutation cycle and ROS-dependent survival signaling. However, cancer cells select mutations to elevate ROS...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Variar, Gokul, Pant, Tarun, Singh, Apoorva, Ravichandran, Abinaya, Swami, Sushant, Kalyanaraman, Balaraman, Dhanasekaran, Anuradha
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398517/
https://ncbi.nlm.nih.gov/pubmed/28426671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174546
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