Effect of mitochondrially targeted carboxy proxyl nitroxide on Akt-mediated survival in Daudi cells: Significance of a dual mode of action

Vicious cycles of mutations and reactive oxygen species (ROS) generation contribute to cancer progression. The use of antioxidants to inhibit ROS generation promotes cytostasis by affecting the mutation cycle and ROS-dependent survival signaling. However, cancer cells select mutations to elevate ROS...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Variar, Gokul, Pant, Tarun, Singh, Apoorva, Ravichandran, Abinaya, Swami, Sushant, Kalyanaraman, Balaraman, Dhanasekaran, Anuradha
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398517/
https://ncbi.nlm.nih.gov/pubmed/28426671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174546
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